What real loss is defined as
Not money, not health, not reputation.
فَٱعْبُدُوا۟ مَا شِئْتُم مِّن دُونِهِۦ ۗ قُلْ إِنَّ ٱلْخَـٰسِرِينَ ٱلَّذِينَ خَسِرُوٓا۟ أَنفُسَهُمْ وَأَهْلِيهِمْ يَوْمَ ٱلْقِيَـٰمَةِ ۗ أَلَا ذَٰلِكَ هُوَ ٱلْخُسْرَانُ ٱلْمُبِينُ
…qul inna-l-khāsirīna-lladhīna khasirū anfusahum wa ahlīhim yawma-l-qiyāmah, alā dhālika huwa-l-khusrānu-l-mubīn.
So worship what you will besides Him." Say, "Indeed, the losers are the ones who will lose themselves and their families on the Day of Resurrection. Unquestionably, that is the manifest loss."
Source
The Qur'an · 39:15
Qur'an
- Qur'anic text in the Uthmani script via Quran.com; translation: Saheeh International